An instrument sterilization container may include a base, a lid, a retention mechanism extending out from a base floor of the base, a first support mechanism extending out from a lid top of the lid, and a second support mechanism extending out from the base floor. A reusable instrument handle may be disposed between the first support mechanism, the second support mechanism, the retention mechanism, and a portion of the base. The portion of the base and the retention mechanism may be configured to prevent an actuation structure of the reusable instrument handle from extending during a sterilization of the reusable instrument handle in a medical autoclave. The first support mechanism and the second support mechanism may be configured to prevent the actuation structure from expanding during a sterilization of the reusable instrument handle in a medical autoclave.