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ε-polylysine conjugate and use thereof
专利权人:
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング
发明人:
キューベルベック,アルミン,ラルビク,グレゴー,ミーア,ウァルター,バイヤー,バルブロ,ハーベルコルン,ウーヴェー,キューベルベック,アルミン,ラルビク,グレゴー,ミーア,ウァルター,バイヤー,バルブロ,ハーベルコルン,ウーヴェー
申请号:
JP2012520925
公开号:
JP5819824B2
申请日:
2010.07.09
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
Conjugate comprises at least one carboxyl group-containing compound and an oligomer, where the oligomer: comprises peptidically crosslinked monomer units; is formed from more than 50%, relative to the number of monomer units, of epsilon -lysine monomer units; or comprises at least 10 consecutive monomer units that are formed from at least up to 70%, relative to the number of monomer units, of epsilon -lysine monomer units. Independent claims are included for: (1) the preparation of the conjugate comprising providing the oligomers, as above per se, and conjugating at least one optionally activated carboxylic group-containing compound to the oligomer; and (2) a kit, for preparing pharmaceutical composition (preferably a therapeutic or image enhancing composition), comprising the above conjugate.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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