Some embodiments of a biopsy system are configured to obtain a sample of tissue from an internal body site, such as a portion of myocardial tissue from a heart chamber wall. The biopsy system may include a catheter device having tissue collection jaws and an inflatable balloon disposed along a distal portion. Also, the biopsy system may include a pressure sensor device to detect the pressure within the heart chamber in which the tissue collection jaws are disposed.
