Edward S. Boyden;Dennis J. Rivet;Lowell L. Wood, Jr.;Victoria Y. H. Wood;Roderick A. Hyde;Muriel Y. Ishikawa;Elizabeth A. Sweeney;Mahalaxmi Gita Bangera
发明人:
Mahalaxmi Gita Bangera,Edward S. Boyden,Roderick A. Hyde,Muriel Y. Ishikawa,Dennis J. Rivet,Elizabeth A. Sweeney,Lowell L. Wood, Jr.,Victoria Y. H. Wood
申请号：
US12387325
公开号：
US08753677B2
申请日:
2009.04.29
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Described embodiments include a final dosage form for administering a medicament to an animal, an article of manufacture, and method. A described final dosage form includes a dosage portion having a medicament and a release element in a first medicament-release state. The medicament has a first bioavailability to the animal. The release element is modifiable ex vivo to a second medicament-release state by an exposure to a stimulus, wherein the medicament has a second bioavailability to the animal. The final dosage form includes another dosage portion having another medicament and another release element in another first medicament-release state. In the another first medicament-release state, the another medicament has another first bioavailability to the animal. The another release element is modifiable ex vivo to another second medicament-release state by an exposure to another stimulus, wherein the another medicament has another second bioavailability to the animal.
