Jose Ignacio ANDRES GIL,Christa C. Chrovian,Michael A. Letavic,Jason C. Rech,Dale A. Rudolph,Akinola Soyode Johnson
申请号:
US15541040
公开号:
US20180118749A1
申请日:
2015.08.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention is directed to compounds of Formula (I), which includes enantiomer and diasteromers thereof: These compounds are suitable for use in the treatment of diseases associated with P2X7 receptor activity such as diseases of the autoimmune and inflammatory system, diseases of the nervous and neuro-immune system, diseases involved with neuroinflammation of the Central Nervous System (CNS) or diseases of the cardiovascular, metabolic, gastrointestinal and urogenital systems.