MEDPROJECT PHARMA-ENTWICKLUNGS- UND VERTRIEBSGESELLSCHAFT MBH
发明人:
POLZER, HEINZ,ELENA, PIERRE-PAUL,SENGE, JURGEN
申请号：
CA2985897
公开号：
CA2985897A1
申请日:
2016.06.08
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention refers to a drippable ophthalmic gel, said gel having a composition comprising bimatoprost in an amount of 0.003 to 0.03% by weight, polyacrylate in an amount of > 0.2 % by weight, povidone (PVP), dextrane, polyethylene glycols (PEG), carboxymethyl cellulose (CMC) or poly(vinyl alcohol) (PVA) in an amount of 0.2 to 10 % by weight, an isotonizing agent in an amount to produce an osmolality of 200 to 400 mosml/kg, a salt for adjusting the viscosity in an amount of 0.05 to 0.4% by weight, a base in an amount to adjust the pH to 6 to 8 and excipients normally used in ophthalmic gels, having a viscosity in the range of 200 to 2000 mPa·s.
