SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES

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专利权人:

发明人:

申请号：

EP16716585.1

公开号：

EP3283120A1

申请日:

2016.04.15

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Site-specific antibody-drug conjugates are described, in particular conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the form of a linker. The site of conjugation, along with modification of the antibody moiety, allows for improved safety and efficacy of the ADC.

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