Paul A. Algate,Lauren Carter,Jonathan David Clapper,Alexander Gaiger,Jane Mannion,Patricia Dianne McNeill,Nadia Ordonez,Aijun Wang
申请号：
US15269027
公开号：
US20170002088A1
申请日:
2016.09.19
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed are methods and compositions for the detection, diagnosis, prognosis, and therapy of hematological malignancies, and in particular, B cell leukemias, lymphomas and multiple myelomas. Disclosed are compositions, methods and kits for eliciting immune and T cell responses to specific malignancy-related antigenic polypeptides and antigenic polypeptide fragments thereof in an animal. Also disclosed are compositions and methods for use in the identification of cells and biological samples containing one or more hematological malignancy-related compositions, and methods for the detection and diagnosis of such diseases and affected cell types. Also disclosed are diagnostic and therapeutic kits, as well as methods for the diagnosis, therapy and/or prevention of a variety of leukemias and lymphomas.
