The present invention relates to prevention, alleviation, or treatment of intractable epilepsy, especially focal cortical dysplasia (FCD). According to the present invention, it is possible to reduce the number or size of abnormal neurons in the cerebrum.COPYRIGHT KIPO 2020본 발명은 난치성 뇌전증, 예를 들면 국소 피질 이형성증(focal cortical dysplasia, FCD)의 예방, 개선 또는 치료에 관한 것이다.