The present invention is directed to a device for recognition of biological alteration in human tissues using electromagnetic waves in the microwave range, the device comprising: a transmitter device (100) comprising at least one transmitting antenna (101), a transmitter (102), and a power supply (103); a receiving device (200) comprising at least one receiving antenna (201), a receiver (202), a pre-processing module (204), and a power supply (203); and a data processing device (300) comprising a microprocessor (301) and a display (302); wherein the transmitter device (100) and the receiving device (200) are configured to operate at a frequency comprised between 2.0 GHz and 3.0 GHz.In a preferred embodiment, the operating frequency is comprised between 2.3 GHz and 2.5 GHz, and the device is suitable for the detection of a cancer in the human body, for example for the screening of prostate cancer, colorectal cancer, breast cancer, thyroid cancer.The device according to the invention is capable of high sensitivity and accuracy of results and can detect not only the presence, but also the position of a cancer.