KIM, RONALD M.,PARMEE, EMMA R.,SINZ, CHRISTOPHER JOSEPH,ZIOUZINA, OLGA A.
申请号：
CA2753434
公开号：
CA2753434C
申请日:
2010.02.22
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
This inventions relates tocompounds having the structure Formula II and pharmaceutically acceptable saltsthereof which are soluble guanylatecy-clase activators. The compounds are usefulfor treatment or prevention ofcardiovascu-lar diseases, endothelial dysfunction,dias-tolic dysfunction, atherosclerosis,hyper-tension, pulmonary hypertension, anginapectoris, thromboses, restenosis,myocar-dial infarction, strokes, cardiacinsufficien-cy, pulmonary hypertonia, erectiledys-function, asthma bronchiale, chronickid-ney insufficiency, diabetes, or cirrhosis ofthe liver.
