The present invention is related to powder, which contains collagen and ceramide ingredients in body type, cheaply and efficiently made from inedible parts (mainly, their heads) of eels. The present invention provides a manufacturing method of combination of eels collagen and ceramide ingredients in body type. The method includes: (1) A step of using a jet of water to clean eels heads (2) A step of heating eels heads in the water and smash them simultaneously (3) A step of adding enzymes to proceed the enzyme reaction after the temperature cools down stated in Step 2 above (4) A step of stopping the enzyme reaction through heating further the cooling temperature stated in Step 3 above (5) A step of separating filtrate and solid particles through reactants obtained from Step 4 above filtered by screening forms A step of pouring filtrate obtained from Step 5 above into a centrifuge, proceeding separation, and obtaining combination of collagen and ceramide ingredients.本發明係從鰻魚的不可食部分(主要是頭部)廉價且高效地製造包含膠原蛋白及人體型神經醯胺成分的粉末。本發明提供一種包含來自鰻魚的膠原蛋白及人體型神經醯胺成分之組合物的製造方法,其包括:(1)通過噴射水流清洗鰻魚頭部之步驟;(2)在水中加熱鰻魚頭部,同時進行粉碎之步驟;(3)從前述(2)之步驟的溫度冷卻後,添加酶來進行酶反應之步驟;(4)從前述(3)之步驟的冷卻溫度進一步加熱來停止酶反應之步驟;(5)用篩檢程式過濾前述(4)中所獲得的反應物來將濾液與固形物分離之步驟;(6)將前述(5)中所獲得的濾液注入到離心分離器中並進行分離,回收包含膠原蛋白及神經醯胺成分之組合物之步驟。
