Murielle Marie Ellison;Randy Ira Hecht;Mark Leo Michaels;Jeonghoon Sun;Yue-Sheng Li;Agnes Eva Hamburger;Edward John Belouski;Jing Xu
发明人:
Edward John Belouski,Murielle Marie Ellison,Agnes Eva Hamburger,Randy Ira Hecht,Yue-Sheng Li,Mark Leo Michaels,Jeonghoon Sun,Jing Xu
申请号：
US13426460
公开号：
US08835385B2
申请日:
2012.03.21
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, wherein the FGF 21 mutant polypeptides comprise two or more mutations, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.
