THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;VOJTESEK, BORIVOJ;MASARYK MEMORIAL CANCER INSTITUTE;THE UNIVERSITY OF DUND
发明人:
HARRIS, CURTIS C.,FUJITA, KAORI,HORIKAWA, IZUMI,BOURDON, JEAN-CHRISTOPHE,LANE, DAVID P.,VOJTESEK, BORIVOJ
申请号：
CA2705488
公开号：
CA2705488C
申请日:
2008.10.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention provides methods and compositionsfor modulating cell senescence and cell proliferation using isoformsof the p53 tumor suppressor protein. The methods and compositionsof the invention find use in inhibiting cancer cell growth or in generatingpopulations of cells for tissue regeneration through the modulationof cell senescence and proliferation.
