LIN, SHINN ZONG,林欣荣,林欣榮,HARN, HORNG JYH,韩鸿志,韓鴻志,LIU, SHIH PING,刘诗平,劉詩平,FU, RU HUEI,傅如辉,傅如輝,LIN, PO CHENG,林珀丞,CHUANG, MING HSI,庄明熙,莊明熙
申请号：
TW103132044
公开号：
TWI625391B
申请日:
2014.09.17
申请国别(地区):
TW
年份:
2018
代理人:
摘要：
A use of ligustilide is provided, including the use of ligustilide to enhance the therapeutic effect of stem cells, as well as the use of a combination of ligustilide and ligustilide-treated stem cells on stem cell therapy. With the treatment of ligustilide, stem cells can provide an enhanced therapeutic effect. Such treatment especially can increase the expression of differentiation-promoting genes in stem cells, increase the expression of homing-promoting genes in stem cells, and/or decrease the expression of inflammatory genes in stem cells.藁本內酯(ligustilide)之應用，包括使用藁本內酯以提升幹細胞之治療效益，以及於幹細胞治療上併用藁本內酯與經藁本內酯(ligustilide)處理之幹細胞的應用。經由以藁本內酯處理幹細胞，可提升幹細胞的治療效益，尤其可增加幹細胞之促進分化之基因的表現、增加該幹細胞之促進回歸(homing)之基因的表現、及/或降低該幹細胞之發炎基因的表現。
