Ana María Perez Castillo;Carmen Gil Ayuso-Gontan;María Isabe Cadavid Torres;Valle Palomo Ruiz;José Brea Florian;Ana Martínez Gil;María Isabel Loza Garcia;Concepción Perez Martín;Daniel Perez Fernandez
发明人:
Ana Martínez Gil,Carmen Gil Ayuso-Gontan,Valle Palomo Ruiz,Daniel Perez Fernandez,Concepción Perez Martín,Ana María Perez Castillo,María Isabel Loza Garcia,María Isabe Cadavid Torres,José Brea Florian
申请号:
US13499901
公开号:
US20120225879A1
申请日:
2010.10.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is based on the use of a broad family of 5-imino-1,2,4-thiadiazoles as potential new drugs for the treatment of diseases in which PDE7 inhibition is important, specially inflammatory diseases, autoimmune and neurodegenerative disorders. On the other hand, compounds of the 5-imino-1,2,4-thiadiazole family are here described, as well as their synthetic procedures, and they may have great application as drug or drug candidates.Therefore, a first aspect of the present invention is related to a compound of formula (I):