This invention safety is high, prevention of the bone disease and/or the medicine formulation which contains the medicine composition and that composition for remedy, it designates that the health food or the functional food is offered as purpose. Prevention of the bone disease and/or remedy is possible ariruheputanoido chemical compound and its affinity body which are displayed with below-mentioned formula (i) as the active ingredient by containing.(In formula (i), as for R1 and R5, the alkyl group of H, C1 - 3, no functional group which is chosen from the group which consists of the monosaccharide and two sugars R2, as for R3, and R4, the alkyl group of H, OH, C1 - 3, no functional group which is chosen from the group which consists of the monosaccharide and two sugars R5, in addition, connecting to the meta position vis-a-vis the hepuchiren basis of the other aryl basis, it is possible to form ring.)本発明は、安全性の高い、骨疾患の予防及び/又は治療用医薬組成物、その組成物を含有する医薬製剤、健康食品、又は機能性食品を提供することを目的とする。下記式(I)で表されるアリールヘプタノイド化合物及びその類縁体を有効成分として含有することにより、骨疾患の予防及び/又は治療が可能である。(式(I)中、R1及びR5は、H、C1~3のアルキル基、単糖及び二糖からなる群から選ばれるいずれかの官能基;R2、R3、及びR4は、H、OH、C1~3のアルキル基、単糖及び二糖からなる群から選ばれるいずれかの官能基;R5は、また、他方のアリール基のヘプチレン基に対してメタ位に結合して環を形成してもよい。)
