Kazuyuki Takahashi;Paul O. Zamora;Louis A. Pena;Xinhua Lin
发明人:
Paul O. Zamora,Louis A. Pena,Xinhua Lin,Kazuyuki Takahashi
申请号：
US12023801
公开号：
US20150353615A9
申请日:
2008.01.31
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Compounds of the present invention of formula I and formula II are disclosed in the specification and wherein the compounds are modulators of Bone Morphogenic Protein activity. Compounds are synthetic peptides having a non-growth factor heparin binding region, a linker, and sequences that bind specifically to a receptor for Bone Morphogenic Protein. Uses of compounds of the present invention in the treatment of bone lesions, degenerative joint disease and to enhance bone formation are disclosed.
