AVCADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM
发明人:
Robert Antoine Francois Marie CHAMULEAU,Ruurdtje HOEKSTRA,Gerardus Adrianus Antonius NIBOURG
申请号:
US14541164
公开号:
US20150073389A1
申请日:
2014.11.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Human hepatocyte cell cultures and their use in bioreactors and bioartificial liver (BAL) systems are provided. The cells have constitutive liver-specific metabolic activity resembling that of freshly isolated human hepatocytes. The hepatocyte cells and BAL systems can be used to treat patients suffering from acute liver failure, end-stage liver disease, or acute-on-chronic liver disease.