PROBLEM TO BE SOLVED: To provide an agent or method for promoting contraction of a collagen gel or improving a skin condition, and to provide a method for selecting the agent.SOLUTION: The method for selecting the collagen gel contraction promoter or the skin condition improving agent includes following steps of: adding a test material to a substrate having a mechanosensor measuring an activation or expression of the mechanosensor and evaluating a promotion effect on the collagen gel or improvement effect on the skin condition based on the activation or expression.COPYRIGHT: (C)2012,JPO&INPIT【課題】コラーゲンゲル収縮促進又は皮膚状態改善のための剤又は方法の提供、ならびに当該剤の選択方法の提供。【解決手段】以下の工程を含む、コラーゲンゲル収縮促進剤又は皮膚状態改善剤の選択方法:メカノセンサーを有する基質に試験物質を添加する工程;当該メカノセンサーの活性又は発現を測定する工程;及び、当該活性又は発現に基づいて当該試験物質のコラーゲンゲル収縮促進効果又は皮膚状態改善効果を評価する工程。【選択図】なし
