AGENT THÉRAPEUTIQUE POUR UNE MALADIE INFLAMMATOIRE DE L'INTESTIN

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专利权人:

Stemrim Inc.;Osaka University

发明人:

申请号：

EP18882661.4

公开号：

EP3718561A1

申请日:

2018.11.30

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present inventors discovered that an HMGB1 fragment peptide having a specific amino acid sequence exhibits an effect of suppressing weight loss and an effect of suppressing shortening of the large intestine and mucosal damage in an animal model of inflammatory bowel diseases. Based on these findings, pharmaceutical compositions for the prevention and/or treatment of inflammatory bowel diseases, which comprise the HMGB1 fragment peptide having the specific amino acid sequence are provided.

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