Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
发明人:
Thomas Tuschl,Javier Martinez,Agnieszka Patkaniowska,Henning Urlaub,Reinhard Luehrmann
申请号:
US15258603
公开号:
US10023865B2
申请日:
2016.09.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.