Methods, systems and devices are disclosed for the efficient and coordinated delivery of COPD treatment to the lung(s) of a patient. A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to an airway of a patient in a constrained configuration and to change to a tissue-compressing configuration when deployed at a target zone to provide treatment to the lung airway. The invention further discloses a method of quickly and efficiently deploying the device using a single coordinated motion or signal which may be particularly useful when multiple devices are deployed at multiple target zones.