The Board of Trustees of the University of Illinois
发明人:
Rajeshwari T Mehta,Brad N Taylor,Tohru Yamada,Craig W Beattie,Tapas K Das Gupta,Ananda M Chakrabarty
申请号：
US13763962
公开号：
US20130210731A1
申请日:
2013.02.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to compositions comprising cupredoxins, and their use to inhibit angiogenesis in mammalian cells, tissues, and animals, and particularly the angiogenesis that accompanies tumor development and particularly in humans. Specifically, the present invention relates to compositions comprising the cupredoxin(s), and or peptides that are variants, derivatives or structural equivalents of cupredoxins, which retain the ability to inhibit angiogenesis in mammalian cells, tissues or animals. These compositions may be peptides or pharmaceutical compositions, among others. The compositions of the invention may be used to treat any pathological condition that has as a symptom or cause, inappropriate angiogenesis, and particularly inappropriate angiogenesis related to tumor development.
