Safety assembly (1) for the medical technique, in particular blood collection, comprising a handling device (2) with a hollow shaped main body part (6), which has a distal end (8) with a clamping extension (10) and an open configuration proximal end (9) that is configured to accommodate at least a part of a collection container, and extending between the distal end (8) and the proximal end (9 ) a longitudinal axis (7), a protection device (4) with an annular base part (19) as well as a protection element (18) pivotally connected with the base part (19), which can pivot from a release position to a protection position to cover at least partially in the protection position a needle arrangement (4) that can be arranged in the handling device (2), the base piece (19) being held in the extension clamping (10) of the d operating device (2) rotatably around the longitudinal axis (7), a locking device (26) with at least a first locking element (27) in the operating device (2) as well as at least a second element of blocking (28) in the protection device (4), being fixed, when the first and second locking elements (27, 28) are engaged, a relative position of the protection device (4) with respect to the handling device ( 2), and the at least first locking element (27) provided in the operating device (2) being arranged, with respect to the clamping extension (10), in radial direction with respect to the longitudinal axis (7), spaced apart of the clamping extension (10), as well as in the radial direction, with respect to the longitudinal axis (7), on the side of the base part (19) away from the longitudinal axis (7), characterized in that the at least second element lock (28) is arranged or configured in the base piece (19) of the protection device (4), on the side of the base piece (19) away from the longitudinal axis (7) therein, and the at least second locking element (28) is projectively shaped in the direction radial of the base piece (19), an established blocking force