MARIO VARASI,GIACOMO CARENZI,SAVERIO MINUCCI,DANIELE FANCELLI,SIMON PLYTE,MARCO BALLARINI,ANNA CAPPA,GILLES PAIN,MANUELA VILLA
申请号：
IL21225011
公开号：
IL212250A
申请日:
2011.04.11
申请国别(地区):
IL
年份:
2015
代理人:
摘要：
Acrylamido derivatives useful as therapeutic agents, particularly for the prevention and/or treatment of diseases and conditions associated with the activity of the mitochondrial permeability transition pore (MPTP), such as the diseases characterized by ischemia/reperfusion, oxidative or degenerative tissue damage, are herein described. These compounds belong to the structural formula (I) wherein R, R', R", W and a are as defined in the specification. The invention also relates to the preparation of these compounds, as well as to pharmaceutical compositions comprising them.
