ANTICORPS MONOCLONAL CAPABLE DE RECONNAITRE LA PROTEINE L2 DU PAPILLOMAVIRUS HUMAIN (HPV) ET PROCEDE DE MESURE DU TITRE EN ANTICORPS NEUTRALISANT LE HPV L'EMPLOYANT
The present invention relates to the development of a monoclonal antibodywhich has binding activity to many high-risk types of HPV, etc. The presentinventionalso provides a simple and high-throughput method for measuring cross-neutralizingantibody titers, which is used for assay of cross-neutralizing antibodyagainst HPV inserum samples from subjects, etc. The method of the present invention formeasuringcross-neutralizing antibody titers comprises the steps of: preparing amonoclonalantibody against a peptide having a specific amino acid sequence common tohigh-risktypes of HPV; and assaying cross-neutralizing antibody using this monoclonalantibody.