2-DISUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES

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专利权人:

发明人:

Vinay Girijavallabhan,Stephane Bogen,Weidong Pan,Qun Dang,Ian Davies

申请号：

US14436687

公开号：

US20160045526A1

申请日:

2013.10.11

申请国别(地区):

US

年份:

2016

代理人:

摘要：

2′-disubstituted substituted nucleoside derivatives of formula (I) and pharmaceutically acceptable salts thereof are disclosed: (1), wherein A is N3 or NH2 and X, Y, R1, R2, R3, R4, R5 and R18 are as defined herein. Compositions comprising at least one 2′-disubstituted nucleoside derivative, and methods of using the 2′-disubstituted nucleoside derivatives for treating or preventing HCV infection in a patient are disclosed.

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