Disclosed is a system of education, monitoring and advising on glucose testing, diet, exercise and drug administration using a device which is carried by the patient and which is capable of: blood glucose testing, displaying messages advising the patient to initiate blood glucose testing, and of recording the results of the test； of displaying advice or further queries based on analysis of the results, and displaying messages relating to advice, education and/or or further queries based on the analysis. The messages are optimized based on their effectiveness in bringing about a favorable response in the patient's blood glucose level or based on other clinical endpoints.
