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Inhibitors of fatty acid amide hydrolase
专利权人:
Infinity Pharmaceuticals; Inc.
发明人:
Alfredo C. Castro,Catherine A. Evans,Louis Grenier,Michael J. Grogan
申请号:
US13970495
公开号:
US08802119B2
申请日:
2013.08.19
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided herein are compounds of formula (I): or pharmaceutically acceptable salts, solvates or prodrugs thereof or mixtures thereof, wherein Z1, Z2, X1, X2, X3, R1, R2 R3, R4, m and n are defined herein. Also provided are pharmaceutically acceptable compositions that include a compound of formula I and a pharmaceutically acceptable excipient. Also provided are methods for treating an FAAH-mediated disorder comprising administering to a subject in need thereof a therapeutically effective amount of a compound or composition of the present invention.
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