A fastener cartridge assembly for use with a circular surgical fastening device. The fastener cartridge assembly includes a cartridge body that has a circular deck. A plurality of fastener cavities is provided in the circular deck. Each fastener cavity includes two cavity ends wherein one cavity end of each of the fastener cavities is positioned on a first circular axis having a first radius and wherein the other cavity end of each fastener cavity is positioned on a second circular axis that has a second radius that differs from the first radius.