The Broad Institute, Inc.;The Brigham and Women's Hospital, Inc.;Massachusetts Institute of Technology
发明人:
Ana Carrizosa Anderson,Asaf Madi,Nandini Acharya,Vijay K. Kuchroo,Aviv Regev
申请号：
US16396461
公开号：
US20190365781A1
申请日:
2019.04.26
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The subject matter disclosed herein is generally directed to modulating T cell dysfunctional and effector states by modulating glucocorticoid and IL-27 signaling. The invention further relates to modulating immune states, such as CD8 T cell immune states, in vivo, ex vivo and in vitro. The invention further relates to diagnostic and screening methods.
