A process includes rupturing plant cells of cannabis by freeze-drying the cannabis at a temperature below 0° C. in order to expose or release one or more chemicals including at least cannabinoids in the plant cells of the cannabis, after rupturing the cannabis plant cells, extracting the one or more chemicals including at least cannabinoids from the cannabis by pressurizing the cannabis in a pressure vessel with along with a solvent, the solvent dissolving the one or more chemicals including at least cannabinoids, followed by depressurizing the cannabis in the pressure vessel, where the depressurizing precipitates the one or more chemicals including at least cannabinoids out of the solvent, and then isolating the one or more chemicals including at least cannabinoids that precipitated from the solvent.
