SCHNUTE, MARK EDWARD,FLICK, ANDREW CHRISTOPHER,JONES, PETER,KAILA, NEELU,MENTE, SCOT RICHARD,TRZUPEK, JOHN DAVID,VAZQUEZ, MICHAEL L.,XING, LI,ZHANG, LIYING,WENNERSTAL, GORAN MATTIAS,ZAMARATSKI, EDOUAR
申请号:
CA2975060
公开号:
CA2975060C
申请日:
2016.01.29
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention provides methoxy-substituted pyrrolopyridines of theFormula I:wherein X, W and R1 are as described herein, pharmaceutical compositionsthereof,methods of modulating ROR.gamma. activity and/or reducing the amount of IL-17in asubject, and methods of treating various medical disorders using suchpyrrolopyridines and pharmaceutical compositions thereof.