As for this invention, general formula (i): (i)[In formula: R, R, R, R, R, R, R, R, R, R, and X as in definition are in the patent claim]It regards the use of the said chemical compound which so is shown and the disease, especially preparation manner of halo phenoxy benzamide derivative chemical compound and the said chemical compound displacement, as a constituent and a combination and the independent material which include the said chemical compound or combining with the other active ingredient, the excessive vegetating disease and/or in the disposal of the vascular new life disease or producing the medicine constituent for preventing.本発明は、一般式(I):(I)[式中:R1、R2、R3、R3a、R4、R5、R6、Ra、Rb、Rc、およびXは、特許請求の範囲に定義のとおりである]で示される置換されたハロフェノキシベンズアミド誘導体化合物、該化合物の調製方法、該化合物を含む組成物および組み合わせ物ならびに単独の物質としてまたは他の活性成分と組み合わせて、疾患、特に、過剰増殖性疾患および/または血管新生疾患の処置または予防のための医薬組成物の製造における該化合物の使用に関する。