HBV EPITOPE REACTIVE EXOGENOUS T CELL RECEPTOR (TCR) AND USES THEREOF

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专利权人:

AGENCY FOR SCIENCE; TECHNOLOGY AND RESEARCH

发明人:

BERTOLETTI, ANTONIO,GEHRING, ADAM

申请号：

EP09742949

公开号：

EP2288700A4

申请日:

2009.05.07

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.

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