Pixel array medical devices, systems and methods are described for skingrafting and skinresection procedures. The procedures involve applying a scalpet array to atarget skin site.The scalpet array comprises scalpets positioned on an investing plate. Skinpixels arecircumferentially incised at a target skin site by applying a load via thescalpet array ontosubjacent skin surface that includes the target skin site. Incised skin pixelsare captured on anadherent substrate, where the incised skin pixels are extruded through thescalpet array. Basesof incised skin pixels extruded through the scalpet array are then transected.
