Ella Cathrine Vikinge;Henrik Aronsson;Elin Engström;Oskar Axelsson
发明人:
Ella Cathrine Vikinge,Elin Engström,Henrik Aronsson,Oskar Axelsson
申请号:
US13319327
公开号:
US20120114731A1
申请日:
2010.05.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A multilayer protein film has a mass of greater than 0.5 μg/cm2 and consists essentially of protein. A drug delivery device comprises the multilayer protein film onto which a pharmaceutically active agent can be loaded. A biomedical implant comprises an implant substrate and the multilayer protein film on at least a portion of the implant substrate surface. A method of making a multilayer protein film having a mass of greater than 0.5 μg/cm2 comprises contacting a substrate with a protein solution at a temperature of from about 30° C. to about 95° C., wherein a multilayer protein film having a mass of greater than 0.5 μg/cm2 is formed on the substrate.