MORICONI, ALESSIO A,BIANCHINI, GIANLUCA G,COLAGIOIA, SANDRO S,BRANDOLINI, LAURA L,ARAMINI, ANDREA A,LIBERATI, CHIARA C,BOVOLENTA, SILVIA S,‧莫里克尼,‧比安基尼,‧科拉奇奧亞,‧布蘭多林,‧阿拉米尼,‧里貝拉蒂,‧博沃倫塔
申请号:
HK15103054.0
公开号:
HK1203810A
申请日:
2015.03.25
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
The invention relates to compounds acting as selective antagonists of Transient Receptor Potential cation channel subfamily M member 8 (TRPM8), and having formula (I). Said compounds are useful in the treatment of diseases associated with activity of TRPM8 such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, itch, irritable bowel diseases, cold induced and/or exhacerbated respiratory disorders and urological disorders.