צורות פולימורפיות של מלח נתרן של 4–טרט–בוטיל–n–[4–כלורו–2–(1–אוקסי–פירידין–4–קרבוניל)–פניל]–בנזן סולפונאמיד

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专利权人:

CHEMOCENTRYX INC.

发明人:

申请号：

IL23059914

公开号：

IL230599D0

申请日:

2014.01.22

申请国别(地区):

IL

年份:

2014

代理人:

摘要：

Disclosed are novel polymorphic solvated and desolvated forms of the sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)phenyl]-benzenesulfonamide. One embodiment of the present invention is directed to a crystalline sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]benzenesulfonamide (hereinafter &ldquo；Compound A-1,4-dioxane/water solvate&rdquo；), wherein the crystalline form is characterized by an X-ray powder diffraction pattern comprising diffraction angles (° 28), when measured using Cu Ku radiation, at about 4.0, 8.1, 10.1, 14.2, 16.2, 18.6, 20.3, 24.7, 25.0, and 26.5.

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