METHOD OF PRODUCING PROPYL GALLATE MICROPARTICLE USING SUPERCRITICAL ANTI-SOLVENT PROCESS AND PROPYL GALLATE MICROPARTICLE PRODUCED THEREBY

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专利权人:

NATIONAL TAIWAN UNIVERSITY

发明人:

CHEN, YAN PING,陈延平,陳延平,CHANG, CHIUNG YUN,张琼云,張瓊云

申请号：

TW099139720

公开号：

TW201221154A

申请日:

2010.11.18

申请国别(地区):

TW

年份:

2012

代理人:

摘要：

The present invention applies the supercritical anti-solvent (SAS) process to treat active pharmaceutical ingredient propyl gallate to prepare propyl gallate microparticles. The present invention reduces the average particle size of the active pharmaceutical ingredient propyl gallate from about 500 μm to less than 50 μm and efficiently enhances the anti-oxidation ability thereof.本發明以超臨界反溶劑法,針對原料藥沒食子酸丙酯進行處理,以製備沒食子酸丙酯微粒。本發明可將原料藥沒食子酸丙酯之平均粒徑自約500微米縮小至小於50微米,並有效提升其抗氧化能力。

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/