Sarepta Therapeutics, Inc.;Massachusetts Institute of Technology
发明人:
Justin M. Wolfe,Colin M. Fadzen,Zi-Ning Choo,Rebecca L. Holden,Monica Yao,Gunnar J. Hanson,Bradley L. Pentelute
申请号:
US16756616
公开号:
US20200316210A1
申请日:
2018.10.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are oligonucleotides, cell penetrating peptides, and peptide-oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject oligonucleotides, peptides, and peptide-oligonucleotide-conjugates described herein.