PURPOSE: A composition containing Gymnaster koraiensis extract, fraction thereof, or gymnasterkoreayne B is provided to prevent alcoholic liver damage and to improve liver condition. CONSTITUTION: A pharmaceutical composition for protecting liver contains Gymnaster koraiensis extract as an active ingredient. The extract is isolated using water, alcohol of C1-C4, or mixture solvent thereof. A pharmaceutical composition for protecting liver contains Gymnaster koraiensis fraction as an active ingredient. The fraction is prepared from the Gymnaster koraiensis extract using n-hexane, ethyl acetate, n-butanol, and water in order. A pharmaceutical composition for protecting liver also contains gymnasterkoreayne B of chemical formula 1 as an active ingredient.본 발명은 벌개미취(Gymnasterkoraiensis) 추출물, 분획물 또는 이로부터 분리한 짐나스테르코리아인 B 화합물을 유효성분으로 함유하는 간 보호용 또는 간 기능 개선용 조성물에 관한 것으로서, 간 손상에 대한 간 보호용 또는 간 기능 개선용 약학적 조성물 또는 식품으로 유용하게 이용될 수 있다.
