ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ФАРМИНТЕРПРАЙСЕЗ" (RU)
发明人:
Небольсин Владимир Евгеньевич (RU),Кромова Татьяна Александровна (RU)
申请号：
RU2014109441/04
公开号：
RU2014109441A
申请日:
2014.03.12
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A compound of general formula I: or a pharmaceutically acceptable salt thereof, wherein R is an integer of 0 or 1； n is an integer of 0 or 1； R is H or C-C 1 alkyl； R and R are each independently H, C 1 -C alkyl , -NH, -NHC (= O) CH, OH and -NHC (O) CHCOOH； R is -COOH, -C (O) NH ,, -NH, HN = C (NH) NH-, NHS (O) -, (NH) CHNH- or CHC (O) NH-； where R may be optionally substituted with a substituent selected from the group consisting of benzyl, benzyl-OS (O) -, C-C1-6 alkyl, OH and -NH； Q is Q and R, together with the nitrogen atom to which they are attached, can create a cycle； Q and R together with the -C (O) N- moiety to which they are attached can form a cycle optionally substituted in the amino group with the group -C (O) CH； o is an integer of 0 or 2； p is an integer a number from 0 to 3； R and R each independently represents H, -C (O) NH, -COOH, -CHOH or C-Ci-alkyl-NH； where R and R may optionally be substituted with C-Ci-alkyl, -CH (CH (OH) CH ) (C (O) OCH), -CH (CH (OH) CH) (COOH), -CH (CH (CH)) (C (O) OCH), -CH (CH (CH)) (C (O ) NH), -CH (CH) C (O) OCH, -CH (CH) C (O) NH, -CH (CHCH (CH)) (C (O) OCH), -CH (CHCH (CH)) (C (O) ONH), —CH (CHOH) (COOH), —CH (CH (OH) CH) (C (O) OCH), —CH (CH (OH)) (C (O) OCH), -SCHS (OH) CH, - (CH) OH, - (CH) OH, —CHC (O) NH, —CHC (O) OCH, —CHCOO or —C (O) OCH； R is or where R may optionally be substituted with one or more substituents selected from C 1-6 alkyl, C 1-6 alkoxy, halogen, COOH, pyridyl and 0 O benzyl； or a compound selected from the following compounds: provided that the compound is not selected from the following compounds: 2. The compound or its pharmaceutically acceptable salt according to claim 1, which represents: 3. A method for the prevention or treatment of diseases caused by RNA-containing viruses belonging to the genus enteroviruses, metapneum1. Соединение общей формулы I:или его фармацевтически приемлемая соль,гдеRпредставляет собойиm представляет собой целое число 0 или 1；n представляет собой целое число
