Methods to treat and produce articles of manufacture that are activated with an electromagnetic and electrical charge to produce activated articles of manufacture and formulations are provided garments. One aspect of the invention is directed toward activated garments and apparel. Our results described herein showed that the fabric sample treated with the activation process according to the invention released more electrons than the control sample. The treated fabric samples released electrons with a lower average energy, making the water of the treated fabric sample more prone to release electrons. Another aspect of the invention is directed toward providing methods and activated formulations for treating various aliments. One formulation described is an activated topical formulation for improving the strength and vitality of nails.