AFFITECH RESEARCH AS;PEREGRINE PHARMACEUTICALS, INC.
发明人:
KAVLIE, ANITA,SCHLUNEGGER, KYLE
申请号：
CA2705152
公开号：
CA2705152C
申请日:
2008.11.07
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Disclosed are human antibodies that specifically inhibit VEGF binding to onlyone (VEGFR2) of the two primaryVEGF receptors. The antibodies effectively inhibit angiogenesis and inducetumor regression, and yet have improved safety due totheir specificity. The present invention thus provides new human antibody-based compositions, methods and combined protocols fortreating cancer and other angiogenic diseases. Advantageous immunoconjugatecompositions and methods using the new VEGF-specific human antibodies are also provided.
