A method of controllably directing an elongate device into a vessel network including the steps of: obtaining a tubular component with a tubular wall bounding a passageway and having an aperture between spaced ends directing an introducing member into the vessel network towards a target site placing the introducing member and tubular component in an operative relationship wherein at least a portion of the introducing member resides within the passageway relatively repositioning the introducing member and tubular component by guided movement, one against the other, to place the aperture at an introduction location and directing the device through the passageway to and through the aperture to the target site.