DAWSON, DAVID W.,KURDISTANI, SIAVASH K.,SELIGSON, DAVID B.
申请号：
EP10765132
公开号：
EP2419737A4
申请日:
2010.04.14
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention provides methods of diagnosing and providing a prognosis and therapy for cancer including, but not limited to, pancreatic cancer and responsiveness to thymidylate synthase inhibitor (e.g., 5-FU) therapy, by identifying cancers with altered histone modification patterns selected from the group consisting of H3K4me2, H3K9me2, or H3K18ac.
