EDWARD ROBERTS,HUGH ROSEN,STEVEN BROWN,MIGUEL A. GUERRERO,XUEMEI PENG,RAMULU PODDUTOORI
申请号:
PT09762826
公开号:
PT2291080E
申请日:
2009.05.14
申请国别(地区):
PT
年份:
2015
代理人:
摘要:
Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.