APPLICATION OF 18-METHYL-15β,16β-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONE SYSTEMS IN THE TREATMENT OF MENORRHAGIA, AS WELL AS INTRAUTERINE SYSTEMS CONTAINING 18-METHYL-15β,16β-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONE FOR TREATING UTERINE BLEEDING DISORDERS
The present invention describes intrauterine use of 18-methyl-15&bgr;,16&bgr;-methylene-19-nor-20-spirox-4-en-3-ones of the general formula (1) wherein R6 and R7 are hydrogen or a methylene group, in the treatment of menorrhagia, of uterine haemorrhages in general, and an intrauterine system for said use, comprising a compound of formula 1.본 발명은 월경과다증, 일반적으로 자궁 출혈의 치료를 위한 하기 화학식 1의 18-메틸-15β,16β-메틸렌-19-노르-20-스피록스-4-엔-3-온 시스템의 자궁내 용도, 및 하기 화학식 1의 화합물을 함유하는, 상기 용도를 위한 자궁내 시스템을 기술한다:<;화학식 1>;상기 식에서, R6 및 R7은 수소이거나 또는 α-메틸렌 기를 나타낸다.